Tingkat Kecemasan Pasien Kanker yang Menjalani Kemoterapi di Masa Pandemi Covid-19: Literature Review

Liska Lihawa, Ricky Zainuddin


The high morbidity and mortality of Covid-19 causes fear and anxiety about the risk of exposure to this disease in everyone, including cancer patients. Objective: To identify the anxiety level of cancer patients undergoing chemotherapy during the Covid-19 pandemic. Methods: Article searches through Pubmed, ProQuest, ScienceDirect, Wiley, and Google Scholar identified 20,489 articles, then restricted based on inclusion criteria: a study with samples of cancer patients undergoing chemotherapy during the Covid-19 pandemic; a study that assessed the anxiety level of cancer patients undergoing chemotherapy during the Covid-19 pandemic; published in the last three years; have full text in English and Indonesian, so that 6 articles are obtained. Results: Of the six articles reviewed, one study reported that during Covid-19 all cancer patients undergoing chemotherapy experienced increased anxiety (57%); two studies reported severe anxiety (36.7%; p=0.000 and 33%); two studies reported moderate anxiety with respective scores (22.3; p=0.000; and 18.5; p=0.037); and one study of mild anxiety (25.8% women and 16.8% men; p=0.159). Anxiety experienced by patients is caused by a number of factors, including fear of being infected with Covid-19, type of cancer, age and gender, delays or changes in treatment and treatment plans, excessive exposure to information, uncertainty over the end of Covid-19, lack of understanding and information related to Covid -19, hospital restrictions, and feelings of loneliness. Conclusion: Based on the results of a review of six articles, it was concluded that cancer patients undergoing chemotherapy during the Covid-19 pandemic experienced anxiety that varied from mild to severe anxiety depending on the influencing factors


anxiety level, cancer, chemotherapy, covid-19 pandemic

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Ahn, M. H., Lee, J., Suh, S., Lee, S., Kim, H. J., Shin, Y. W., & Chung, S. (2020). Application of the Stress and Anxiety to Viral Epidemics-6 (SAVE-6) and Coronavirus Anxiety Scale (CAS) to Measure Anxiety in Cancer Patient in Response to Covid-19. Frontiers in Psychology, 11(6041), 1–6. https://doi.org/10.3389/fpsyg.2020.604441

Al-Quteimat, O. M., & Amer, A. M. (2020). The Impact of the COVID-19 Pandemic on Cancer Patients. American Journal of Clinical Oncology: Cancer Clinical Trials, 00(00), 1–4. https://doi.org/10.1097/COC.0000000000000712

Esen, S. A., Acikgoz, U., Yildirim, M., Ucar, G., Ergun, Y., Diriko, M., Bal, O., Algin, E., Esen, I., & Unc, D. (2021). Anxiety, Insomnia and Pandemic Awareness of Cancer Patients Receiving Chemotherapy During the COVID-19 Pandemic Period. International Journal of Hematology and Oncology, 31(2), 1–9. https://doi.org/10.4999/uhod.UHOD

Ganguly, S., Gupta, A., Arora, S., & Arora, N. (2020). Impact of Pandemics. In M. K. Goyal & A. K. Gupta (Eds.), Integrated Risk of Pandemic: Covid-19 Impacts, Resilience and Recommendations (p. 497). Springer Nature Singapore Pte Ltd. https://doi.org/https://doi.org/10.1007/978-981-15-7679-9

Hennessy, M. A., Linehan, A., Cowzer, D., Coyne, Z. L., Fitzpatrick, O., Barrett, F., Dhonaill, R. N., Hennessy, B. T., Grogan, L., Morris, P. G., & Breathnach, O. S. (2021). Chemotherapy in the Covid-19 Era: the Patient’s Perception. Irish Journal of Medical Science, 3(11), 7–12. https://doi.org/https://doi.org/10.1007/s11845-020-02457-3

Hilfiker, L., & Ganguly, S. (2020). A Review of Pandemics. In M. K. Goyal & A. K. Gupta (Eds.), Integrated Risk of Pandemic: Covid-19 Impacts, Resilience and Recommendations (p. 497). Springer Nature Singapore Pte Ltd. https://doi.org/https://doi.org/10.1007/978-981-15-7679-9

International Agency for Research on Cancer. (2021). GLOBOCAN 2020: New Global Cancer Data. International Agency for Research on Cancer (IARC). https://www.uicc.org/news/globocan-2020-new-global-cancer-data

Karacin, C., Bilgetekin, I., B Basal, F., & Oksuzoglu, O. B. (2020). How Does COVID-19 Fear and Anxiety Affect Chemotherapy Adherence in Patients with Cancer. Future Oncology, 16(29), 2283–2293. https://doi.org/10.2217/fon-2020-0592

Kemenkes RI. (2021). Covid-19. Media Informasi Terkini Penyakit Infeksi Emerging. https://infeksiemerging.kemkes.go.id/dashboard/covid-19

Kementerian Kesehatan RI. (2019). Laporan Nasional RISKESDAS 2018. Badan Penelitian dan Pengembangan Kesehatan. https://doi.org/9786023731189

Khng, J. (2021). Managing the Impact of Covid-19 on Cancer Survivors in Singapore. Asia Pacific Journal of Social Work and Development, 31(1–2), 147–151. https://doi.org/10.1080/02185385.2020.1859408

Radji, M. (2017). Mekanisme aksi Molekuler Antibiotik dan Kemoterapi (R. Nirwanto & N. Afifah, Hafshah (eds.)). EGC.

Retnaningsih, D., Auliyak, R., Mariyati, & Purnaningsih, E. (2021). Kecemasan Penderita Kanker Payudara yang Menjalani Kemoterapi Masa Pandemi Covid-19. Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal, 11(1), 157–164. http://journal.stikeskendal.ac.id/index.php/PSKM

Setyani, F. A. R., Bunga, B. D., & Milliani, C. D. (2020). Tingkat Kecemasan Pasien Kanker Payudara Yang Mendapatkan Kemoterapi. Carolus Journal of Nursing, 2(2), 170–176. http://ejournal.stik-sintcarolus.ac.id/%0ATINGKAT

Shams, S., & Mansoor, K. (2020). Covid-19 and Self-Care Measures by Chemotherapy Patients. Asia-Pacific Journal of Oncology Nursing, 7(4), 310–311. https://doi.org/10.4103/apjon.apjon

Sigorski, D., Sobczuk, P., Osmola, M., Kuć, K., Walerzak, A., Wilk, M., Ciszewski, T., Kopeć, S., Hryń, K., Rutkowski, P., Stec, R., Szczylik, C., & Bodnar, L. (2020). Impact of COVID-19 on Anxiety Levels Among Patients With Cancer Actively Treated With Systemic Therapy. ESMO Open, 5(5), 1–8. https://doi.org/10.1136/esmoopen-2020-000970

Stanton, R., To, Q. G., Khalesi, S., Williams, S. L., Alley, S. J., Thwaite, T. L., Fenning, A. S., &Vandelanotte, C. (2020). Depression, Anxiety and Stress during COVID-19: Associations with Changes in Physical Activity, Sleep, Tobacco and Alcohol Use in Australian Adults. International Journal of Environmental Research and Public Health, 17(11), 1–13. https://doi.org/10.3390/ijerph17114065

Tariq, M. J., Almani, M. U., Sherazi, S. A. A., Usman, M., Arif, A. W., Yim, B., & Gupta, S. (2020). Anxiety Due to COVID-19 and Impact on Patients Receiving Chemotherapy in An Inner-City Minority Population. Journal of Clinical Oncology, 38(29), 1–9. https://doi.org/10.1200/JCO.2020.38.29_suppl.108

WHO. (2021). WHO Coronavirus (COVID-19) Dashboard. World Health Organization. https://covid19.who.int/

Yasin, A. I., Topcu, A., Shbair, A. T., Isleyen, Z. S., Ozturk, A., Besiroglu, M., & Türk, H. M. (2021). Anxiety Levels of Breast Cancer Patients in Turkey During the Covid-19 Pandemic. Future Oncology, 1–9. https://doi.org/10.2217/fon-2020-1265

Yildirim, O. A., Poyraz, K., & Erdur, E. (2021). Depression And Anxiety In Cancer Patients Before And During The Sars-Cov-2 Pandemic: Relationship With Delayed Chemotherapy. Quality of Life Research, 30(7), 1903–1912. https://doi.org/10.1007/s11136-021-02795-4

Zhang, J., Yu, H., Gao, Y., Xu, Q., Yin, Y., & Zhou, R. (2020). Prevalence of Anxiety and Depression Among Cancer Patients During the COVID-19 Pandemic: A Systematic Review and Meta-analysis Hongping. ResearchSquare, 1–12. https://doi.org/https://doi.org/10.21203/rs.3.rs-133466/v1

DOI: http://dx.doi.org/10.36565/jab.v11i1.457


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